| Round 1 | |||||
| 7 March | Sydney Roosters | 26 – 24 | South Sydney Rabbitohs | Allianz Stadium | View |
| 8 March | Brisbane Broncos | 30 – 28 | Manly Sea Eagles | Suncorp Stadium | View |
| 9 March | Parramatta Eels | 46 – 8 | Warriors | Parramatta Stadium | View |
| 9 March | Canterbury Bulldogs | 40 – 20 | North Queensland Cowboys | Bluetongue Stadium | View |
| 10 March | Penrith Panthers | 40 – 16 | Canberra Raiders | Centrebet Stadium | View |
| 10 March | Melbourne Storm | 36 – 12 | St George Illawarra Dragons | AAMI Park | View |
| 10 March | Cronulla Sharks | 16 – 29 | Gold Coast Titans | Sharks Stadium | View |
| 11 March | Newcastle Knights | 12 – 22 | Wests Tigers | Hunter Stadium | View |
| Round 2 | |||||
| 14 March | Parramatta Eels | 24 – 32 | Canterbury Bulldogs | ANZ Stadium | View |
| 15 March | St George Illawarra Dragons | 40 – 28 | Brisbane Broncos | WIN Stadium | View |
| 16 March | North Queensland Cowboys | 26 – 16 | Melbourne Storm | 1300SMILES Stadium | View |
| 16 March | Warriors | 20 – 24 | Sydney Roosters | Eden Park | View |
| 17 March | Gold Coast Titans | 24 – 38 | Canberra Raiders | Skilled Park | View |
| 17 March | Wests Tigers | 18 – 30 | Penrith Panthers | Campbelltown Stadium | View |
| 17 March | Manly Sea Eagles | 14 – 26 | Newcastle Knights | Brookvale Oval | View |
| 18 March | South Sydney Rabbitohs | 32 – 18 | Cronulla Sharks | ANZ Stadium | View |
| Round 3 | |||||
| 21 March | Melbourne Storm | 30 – 16 | Canterbury Bulldogs | AAMI Park | View |
| 22 March | Wests Tigers | 40 – 6 | Parramatta Eels | Leichhardt Oval | View |
| 23 March | Gold Coast Titans | 18 – 26 | Manly Sea Eagles | Skilled Park | View |
| 23 March | Sydney Roosters | 22 – 40 | Brisbane Broncos | Allianz Stadium | View |
| 24 March | Cronulla Sharks | 20 – 24 | Warriors | Sharks Stadium | View |
| 24 March | Penrith Panthers | 32 – 14 | South Sydney Rabbitohs | Centrebet Stadium | View |
| 24 March | Canberra Raiders | 44 – 22 | St George Illawarra Dragons | Canberra Stadium | View |
| 25 March | Newcastle Knights | 20 – 26 | North Queensland Cowboys | Hunter Stadium | View |
| Round 4 | |||||
| 28 March | Manly Sea Eagles | 28 – 16 | Wests Tigers | Bluetongue Stadium | View |
| 29 March | Canterbury Bulldogs | 36 – 32 | South Sydney Rabbitohs | ANZ Stadium | View |
| 29 March | Brisbane Broncos | 24 – 28 | Melbourne Storm | Suncorp Stadium | View |
| 30 March | Cronulla Sharks | 36 – 24 | St George Illawarra Dragons | Sharks Stadium | View |
| 31 March | Penrith Panthers | 40 – 12 | Gold Coast Titans | Centrebet Stadium | View |
| 31 March | Newcastle Knights | 26 – 30 | Canberra Raiders | Hunter Stadium | View |
| 1 April | Warriors | 25 – 6 | North Queensland Cowboys | Mt Smart Stadium | View |
| 1 April | Sydney Roosters | 22 – 20 | Parramatta Eels | Allianz Stadium | View |
| Round 5 | |||||
| 5 April | Canterbury Bulldogs | 43 – 30 | Manly Sea Eagles | ANZ Stadium | View |
| 5 April | Gold Coast Titans | 22 – 28 | Brisbane Broncos | Skilled Park | View |
| 6 April | Parramatta Eels | 30 – 30 | Cronulla Sharks | Parramatta Stadium | View |
| 6 April | North Queensland Cowboys | 20 – 32 | Penrith Panthers | 1300SMILES Stadium | View |
| 7 April | St George Illawarra Dragons | 40 – 28 | Newcastle Knights | WIN Jubilee Oval | View |
| 7 April | Warriors | 46 – 14 | South Sydney Rabbitohs | Mt Smart Stadium | View |
| 7 April | Canberra Raiders | 35 – 26 | Sydney Roosters | Canberra Stadium | View |
| 8 April | Melbourne Storm | 24 – 14 | Wests Tigers | AAMI Park | View |
| Round 6 | |||||
| 12 April | Brisbane Broncos | 36 – 34 | North Queensland Cowboys | Suncorp Stadium | View |
| 12 April | Sydney Roosters | 34 – 30 | Canterbury Bulldogs | Allianz Stadium | View |
| 13 April | Newcastle Knights | 14 – 30 | Penrith Panthers | Hunter Stadium | View |
| 13 April | Canberra Raiders | 22 – 22 | Warriors | Canberra Stadium | View |
| 13 April | South Sydney Rabbitohs | 22 – 28 | Melbourne Storm | ANZ Stadium | View |
| 14 April | Manly Sea Eagles | 10 – 26 | Cronulla Sharks | Brookvale Oval | View |
| 14 April | Wests Tigers | 48 – 20 | St George Illawarra Dragons | Sydney Cricket Ground | View |
| 14 April | Gold Coast Titans | 10 – 32 | Parramatta Eels | Skilled Park | View |
| Round 7 | |||||
| 25 April | Sydney Roosters | 54 – 10 | St George Illawarra Dragons | Allianz Stadium | View |
| 25 April | Melbourne Storm | 20 – 36 | Warriors | AAMI Park | View |
| 26 April | Manly Sea Eagles | 12 – 16 | South Sydney Rabbitohs | Brookvale Oval | View |
| 27 April | North Queensland Cowboys | 14 – 18 | Canberra Raiders | 1300SMILES Stadium | View |
| 27 April | Wests Tigers | 22 – 24 | Brisbane Broncos | Campbelltown Stadium | View |
| 28 April | Gold Coast Titans | 8 – 28 | Newcastle Knights | Skilled Park | View |
| 28 April | Cronulla Sharks | 10 – 50 | Canterbury Bulldogs | Bluetongue Stadium | View |
| 29 April | Penrith Panthers | 22 – 18 | Parramatta Eels | Centrebet Stadium | View |
| Round 8 | |||||
| 3 May | Brisbane Broncos | 22 – 20 | South Sydney Rabbitohs | Suncorp Stadium | View |
| 3 May | Canterbury Bulldogs | 28 – 30 | Wests Tigers | ANZ Stadium | View |
| 4 May | Melbourne Storm | 12 – 46 | Canberra Raiders | AAMI Park | View |
| 4 May | Parramatta Eels | 16 – 10 | North Queensland Cowboys | Parramatta Stadium | View |
| 5 May | Warriors | 30 – 32 | Gold Coast Titans | Mt Smart Stadium | View |
| 5 May | Newcastle Knights | 50 – 14 | Cronulla Sharks | Hunter Stadium | View |
| 5 May | Sydney Roosters | 32 – 16 | Penrith Panthers | Allianz Stadium | View |
| 6 May | St George Illawarra Dragons | 28 – 6 | Manly Sea Eagles | WIN Jubilee Oval | View |
| Round 9 | |||||
| 10 May | South Sydney Rabbitohs | 20 – 20 | North Queensland Cowboys | ANZ Stadium | View |
| 10 May | Wests Tigers | 38 – 18 | Cronulla Sharks | Allianz Stadium | View |
| 11 May | Warriors | 34 – 24 | Canterbury Bulldogs | Westpac Stadium | View |
| 11 May | Parramatta Eels | 18 – 40 | Brisbane Broncos | Parramatta Stadium | View |
| 12 May | Canberra Raiders | 40 – 26 | Newcastle Knights | Canberra Stadium | View |
| 12 May | Gold Coast Titans | 20 – 46 | St George Illawarra Dragons | Skilled Park | View |
| 12 May | Penrith Panthers | 10 – 6 | Melbourne Storm | Centrebet Stadium | View |
| 13 May | Manly Sea Eagles | 28 – 24 | Sydney Roosters | Brookvale Oval | View |
| Round 10 | |||||
| 17 May | Brisbane Broncos | 18 – 34 | Gold Coast Titans | Suncorp Stadium | View |
| 17 May | South Sydney Rabbitohs | 26 – 24 | Wests Tigers | ANZ Stadium | View |
| 18 May | St George Illawarra Dragons | 20 – 34 | Parramatta Eels | WIN Stadium | View |
| 18 May | Penrith Panthers | 32 – 38 | Warriors | Centrebet Stadium | View |
| 18 May | North Queensland Cowboys | 14 – 24 | Sydney Roosters | 1300SMILES Stadium | View |
| 19 May | Cronulla Sharks | 24 – 26 | Canberra Raiders | Sharks Stadium | View |
| 19 May | Newcastle Knights | 50 – 26 | Canterbury Bulldogs | Hunter Stadium | View |
| 20 May | Melbourne Storm | 30 – 10 | Manly Sea Eagles | AAMI Park | View |
| Round 11 | |||||
| 24 May | Wests Tigers | 28 – 16 | North Queensland Cowboys | AAMI Park | View |
| 24 May | Canterbury Bulldogs | 40 – 20 | Brisbane Broncos | ANZ Stadium | View |
| 25 May | St George Illawarra Dragons | 18 – 25 | Penrith Panthers | WIN Jubilee Oval | View |
| 25 May | Sydney Roosters | 32 – 10 | Melbourne Storm | Allianz Stadium | View |
| 25 May | Manly Sea Eagles | 20 – 36 | Canberra Raiders | Brookvale Oval | View |
| 26 May | Warriors | 10 – 24 | Newcastle Knights | Mt Smart Stadium | View |
| 26 May | Parramatta Eels | 28 – 30 | Gold Coast Titans | McCredie Park | View |
| 27 May | Cronulla Sharks | 10 – 34 | South Sydney Rabbitohs | Sharks Stadium | View |
| Round 12 | |||||
| 31 May | Canterbury Bulldogs | 22 – 44 | St George Illawarra Dragons | Belmore Sports Ground | View |
| 1 June | South Sydney Rabbitohs | 22 – 30 | Newcastle Knights | ANZ Stadium | View |
| 2 June | Gold Coast Titans | 34 – 32 | North Queensland Cowboys | Skilled Park | View |
| 3 June | Brisbane Broncos | 20 – 46 | Warriors | Suncorp Stadium | View |
| Canberra Raiders | BYE | ||||
| Cronulla Sharks | BYE | ||||
| Manly Sea Eagles | BYE | ||||
| Melbourne Storm | BYE | ||||
| Parramatta Eels | BYE | ||||
| Penrith Panthers | BYE | ||||
| Sydney Roosters | BYE | ||||
| Wests Tigers | BYE |
| Round 13 | |||||
| 7 June | Parramatta Eels | 22 – 24 | Sydney Roosters | Parramatta Stadium | View |
| 8 June | Newcastle Knights | 24 – 10 | St George Illawarra Dragons | Hunter Stadium | View |
| 8 June | North Queensland Cowboys | 24 – 24 | Canterbury Bulldogs | 1300SMILES Stadium | View |
| 9 June | Warriors | 52 – 20 | Manly Sea Eagles | Mt Smart Stadium | View |
| 9 June | Penrith Panthers | 50 – 12 | Wests Tigers | Centrebet Stadium | View |
| 9 June | Melbourne Storm | 34 – 10 | Cronulla Sharks | AAMI Park | View |
| 10 June | Canberra Raiders | 38 – 28 | Brisbane Broncos | Canberra Stadium | View |
| Gold Coast Titans | BYE | ||||
| South Sydney Rabbitohs | BYE |
| Round 14 | |||||
| 14 June | St George Illawarra Dragons | 30 – 14 | North Queensland Cowboys | WIN Stadium | View |
| 14 June | Manly Sea Eagles | 26 – 32 | Canterbury Bulldogs | Brookvale Oval | View |
| 15 June | South Sydney Rabbitohs | 40 – 26 | Gold Coast Titans | Redfern Oval | View |
| 15 June | Canberra Raiders | 32 – 18 | Penrith Panthers | Canberra Stadium | View |
| 15 June | Cronulla Sharks | 16 – 30 | Parramatta Eels | Sharks Stadium | View |
| 16 June | Melbourne Storm | 36 – 8 | Newcastle Knights | AAMI Park | View |
| 16 June | Sydney Roosters | 31 – 26 | Warriors | Allianz Stadium | View |
| 17 June | Brisbane Broncos | 16 – 38 | Wests Tigers | Suncorp Stadium | View |
| Round 15 | |||||
| 21 June | Canterbury Bulldogs | 23 – 16 | Sydney Roosters | ANZ Stadium | View |
| 22 June | Wests Tigers | 36 – 24 | Canberra Raiders | Campbelltown Stadium | View |
| 23 June | Parramatta Eels | 18 – 12 | South Sydney Rabbitohs | ANZ Stadium | View |
| 24 June | Gold Coast Titans | 18 – 24 | Melbourne Storm | Skilled Park | View |
| Brisbane Broncos | BYE | ||||
| Cronulla Sharks | BYE | ||||
| Manly Sea Eagles | BYE | ||||
| Newcastle Knights | BYE | ||||
| North Queensland Cowboys | BYE | ||||
| Penrith Panthers | BYE | ||||
| St George Illawarra Dragons | BYE | ||||
| Warriors | BYE |
| Round 16 | |||||
| 29 June | South Sydney Rabbitohs | 22 – 12 | Canberra Raiders | Aubrey Keech Reserve | View |
| 29 June | Wests Tigers | 25 – 16 | Melbourne Storm | Leichhardt Oval | View |
| 29 June | Penrith Panthers | 14 – 18 | St George Illawarra Dragons | Centrebet Stadium | View |
| 30 June | Newcastle Knights | 10 – 22 | Gold Coast Titans | Hunter Stadium | View |
| 30 June | Warriors | 34 – 28 | Brisbane Broncos | Mt Smart Stadium | View |
| 30 June | North Queensland Cowboys | 28 – 12 | Cronulla Sharks | 1300SMILES Stadium | View |
| 1 July | Sydney Roosters | 34 – 6 | Manly Sea Eagles | Allianz Stadium | View |
| Canterbury Bulldogs | BYE | ||||
| Parramatta Eels | BYE |
| Round 17 | |||||
| 5 July | Melbourne Storm | 18 – 34 | Brisbane Broncos | AAMI Park | View |
| 5 July | Cronulla Sharks | 34 – 22 | Wests Tigers | Remondis Stadium | View |
| 6 July | Canterbury Bulldogs | 26 – 14 | Newcastle Knights | Belmore Sports Ground | View |
| 6 July | South Sydney Rabbitohs | 40 – 38 | Warriors | Redfern Oval | View |
| 6 July | St George Illawarra Dragons | 26 – 48 | Sydney Roosters | WIN Jubilee Oval | View |
| 7 July | Canberra Raiders | 34 – 32 | North Queensland Cowboys | Canberra Stadium | View |
| 7 July | Gold Coast Titans | 12 – 22 | Penrith Panthers | Ned Byrne Oval | View |
| 8 July | Manly Sea Eagles | 34 – 30 | Parramatta Eels | Brookvale Oval | View |
| Round 18 | |||||
| 12 July | Brisbane Broncos | 22 – 12 | Cronulla Sharks | Suncorp Stadium | View |
| 13 July | Parramatta Eels | 10 – 44 | Penrith Panthers | Parramatta Stadium | View |
| 13 July | North Queensland Cowboys | 30 – 20 | Manly Sea Eagles | Jack Manski Oval | View |
| 14 July | Canterbury Bulldogs | 26 – 22 | Melbourne Storm | ANZ Stadium | View |
| Canberra Raiders | BYE | ||||
| Gold Coast Titans | BYE | ||||
| Newcastle Knights | BYE | ||||
| South Sydney Rabbitohs | BYE | ||||
| St George Illawarra Dragons | BYE | ||||
| Sydney Roosters | BYE | ||||
| Warriors | BYE | ||||
| Wests Tigers | BYE |
| Round 19 | |||||
| 19 July | Wests Tigers | 12 – 22 | Warriors | Leichhardt Oval | View |
| 20 July | Canberra Raiders | 46 – 6 | Parramatta Eels | Canberra Stadium | View |
| 20 July | Sydney Roosters | 24 – 26 | Cronulla Sharks | Allianz Stadium | View |
| 21 July | Penrith Panthers | 30 – 4 | Newcastle Knights | Centrebet Stadium | View |
| 21 July | Manly Sea Eagles | 28 – 35 | Gold Coast Titans | Brookvale Oval | View |
| 22 July | South Sydney Rabbitohs | 28 – 16 | St George Illawarra Dragons | ANZ Stadium | View |
| Brisbane Broncos | BYE | ||||
| Canterbury Bulldogs | BYE | ||||
| Melbourne Storm | BYE | ||||
| North Queensland Cowboys | BYE |
| Round 20 | |||||
| 26 July | North Queensland Cowboys | 44 – 32 | Brisbane Broncos | 1300SMILES Stadium | View |
| 26 July | Canterbury Bulldogs | 54 – 18 | Parramatta Eels | ANZ Stadium | View |
| 27 July | St George Illawarra Dragons | 12 – 18 | Canberra Raiders | WIN Stadium | View |
| 27 July | Gold Coast Titans | 26 – 44 | South Sydney Rabbitohs | Skilled Park | View |
| 28 July | Warriors | 20 – 16 | Melbourne Storm | Mt Smart Stadium | View |
| 28 July | Cronulla Sharks | 30 – 8 | Penrith Panthers | Remondis Stadium | View |
| 28 July | Newcastle Knights | 18 – 44 | Sydney Roosters | Hunter Stadium | View |
| 29 July | Wests Tigers | 40 – 22 | Manly Sea Eagles | Campbelltown Stadium | View |
| Round 21 | |||||
| 2 August | Newcastle Knights | 52 – 10 | Brisbane Broncos | Hunter Stadium | View |
| 2 August | Penrith Panthers | 30 – 36 | Sydney Roosters | Centrebet Stadium | View |
| 3 August | Warriors | 34 – 14 | Cronulla Sharks | Mt Smart Stadium | View |
| 3 August | Parramatta Eels | 22 – 52 | Manly Sea Eagles | Parramatta Stadium | View |
| 3 August | North Queensland Cowboys | 34 – 16 | South Sydney Rabbitohs | 1300SMILES Stadium | View |
| 4 August | Canberra Raiders | 46 – 22 | Melbourne Storm | Canberra Stadium | View |
| 4 August | Gold Coast Titans | 32 – 42 | Wests Tigers | Skilled Park | View |
| 5 August | St George Illawarra Dragons | 12 – 40 | Canterbury Bulldogs | WIN Jubilee Oval | View |
| Round 22 | |||||
| 9 August | Melbourne Storm | 28 – 29 | South Sydney Rabbitohs | AAMI Park | View |
| 9 August | Parramatta Eels | 34 – 52 | Wests Tigers | Parramatta Stadium | View |
| 10 August | Sydney Roosters | 32 – 38 | Canberra Raiders | Allianz Stadium | View |
| 10 August | Cronulla Sharks | 26 – 24 | Newcastle Knights | Remondis Stadium | View |
| 11 August | Manly Sea Eagles | 36 – 36 | Warriors | Bluetongue Stadium | View |
| 11 August | Brisbane Broncos | 30 – 28 | St George Illawarra Dragons | Suncorp Stadium | View |
| 11 August | Penrith Panthers | 18 – 22 | North Queensland Cowboys | Centrebet Stadium | View |
| 12 August | Canterbury Bulldogs | 54 – 20 | Gold Coast Titans | ANZ Stadium | View |
| Round 23 | |||||
| 16 August | Brisbane Broncos | 36 – 30 | Parramatta Eels | Suncorp Stadium | View |
| 16 August | South Sydney Rabbitohs | 38 – 18 | Manly Sea Eagles | Bluetongue Stadium | View |
| 17 August | Canberra Raiders | 12 – 62 | Canterbury Bulldogs | Canberra Stadium | View |
| 17 August | North Queensland Cowboys | 52 – 14 | Gold Coast Titans | 1300SMILES Stadium | View |
| 17 August | St George Illawarra Dragons | 16 – 24 | Cronulla Sharks | WIN Stadium | View |
| 18 August | Warriors | 14 – 32 | Penrith Panthers | Mt Smart Stadium | View |
| 18 August | Newcastle Knights | 22 – 30 | Melbourne Storm | Hunter Stadium | View |
| 19 August | Wests Tigers | 32 – 18 | Sydney Roosters | Allianz Stadium | View |
| Round 24 | |||||
| 23 August | South Sydney Rabbitohs | 26 – 48 | Canterbury Bulldogs | ANZ Stadium | View |
| 23 August | Penrith Panthers | 38 – 24 | Brisbane Broncos | Centrebet Stadium | View |
| 24 August | St George Illawarra Dragons | 34 – 16 | Wests Tigers | Sydney Cricket Ground | View |
| 24 August | Gold Coast Titans | 12 – 44 | Warriors | Skilled Park | View |
| 24 August | North Queensland Cowboys | 30 – 22 | Newcastle Knights | 1300SMILES Stadium | View |
| 25 August | Canberra Raiders | 52 – 38 | Manly Sea Eagles | Canberra Stadium | View |
| 25 August | Melbourne Storm | 24 – 38 | Parramatta Eels | AAMI Park | View |
| 26 August | Cronulla Sharks | 20 – 22 | Sydney Roosters | Remondis Stadium | View |
| Round 25 | |||||
| 30 August | Brisbane Broncos | 38 – 6 | Newcastle Knights | Suncorp Stadium | View |
| 30 August | Wests Tigers | 12 – 16 | South Sydney Rabbitohs | Allianz Stadium | View |
| 31 August | Warriors | 16 – 26 | Canberra Raiders | Mt Smart Stadium | View |
| 31 August | Canterbury Bulldogs | 22 – 46 | Penrith Panthers | ANZ Stadium | View |
| 31 August | Manly Sea Eagles | 30 – 18 | Melbourne Storm | Brookvale Oval | View |
| 1 September | Cronulla Sharks | 36 – 20 | North Queensland Cowboys | Remondis Stadium | View |
| 1 September | Sydney Roosters | 34 – 20 | Gold Coast Titans | Allianz Stadium | View |
| 2 September | Parramatta Eels | 22 – 22 | St George Illawarra Dragons | ANZ Stadium | View |
| Round 26 | |||||
| 5 September | Brisbane Broncos | 32 – 48 | Canterbury Bulldogs | Suncorp Stadium | View |
| 6 September | South Sydney Rabbitohs | 20 – 28 | Sydney Roosters | ANZ Stadium | View |
| 7 September | St George Illawarra Dragons | 48 – 4 | Warriors | WIN Stadium | View |
| 7 September | Melbourne Storm | 30 – 10 | Gold Coast Titans | AAMI Park | View |
| 7 September | North Queensland Cowboys | 14 – 48 | Wests Tigers | 1300SMILES Stadium | View |
| 8 September | Manly Sea Eagles | 18 – 30 | Penrith Panthers | Brookvale Oval | View |
| 8 September | Newcastle Knights | 46 – 18 | Parramatta Eels | Hunter Stadium | View |
| 8 September | Canberra Raiders | 36 – 34 | Cronulla Sharks | Canberra Stadium | View |