| Round 1 | |||||
| 12 March | Parramatta Eels | 24 – 18 | St George Illawarra Dragons | Parramatta Stadium | View |
| 12 March | Brisbane Broncos | 12 – 14 | North Queensland Cowboys | Suncorp Stadium | View |
| 13 March | Canterbury Bulldogs | 24 – 32 | Newcastle Knights | ANZ Stadium | View |
| 13 March | Cronulla Sharks | 22 – 36 | Melbourne Storm | Toyota Stadium | View |
| 13 March | Penrith Panthers | 42 – 26 | Canberra Raiders | CUA Stadium | View |
| 14 March | Gold Coast Titans | 36 – 26 | Warriors | Skilled Park | View |
| 14 March | South Sydney Rabbitohs | 30 – 26 | Sydney Roosters | ANZ Stadium | View |
| 15 March | Wests Tigers | 12 – 20 | Manly Sea Eagles | Sydney Football Stadium | View |
| Round 2 | |||||
| 19 March | St George Illawarra Dragons | 12 – 10 | Canterbury Bulldogs | WIN Stadium | View |
| 19 March | South Sydney Rabbitohs | 16 – 22 | Gold Coast Titans | ANZ Stadium | View |
| 20 March | Warriors | 30 – 30 | Cronulla Sharks | Mt Smart Stadium | View |
| 20 March | Newcastle Knights | 10 – 62 | Melbourne Storm | EnergyAustralia Stadium | View |
| 20 March | North Queensland Cowboys | 38 – 5 | Penrith Panthers | Dairy Farmers Stadium | View |
| 21 March | Parramatta Eels | 16 – 32 | Manly Sea Eagles | Parramatta Stadium | View |
| 21 March | Sydney Roosters | 26 – 20 | Wests Tigers | Sydney Football Stadium | View |
| 22 March | Canberra Raiders | 58 – 32 | Brisbane Broncos | Canberra Stadium | View |
| Round 3 | |||||
| 26 March | Wests Tigers | 56 – 24 | Parramatta Eels | Sydney Football Stadium | View |
| 26 March | St George Illawarra Dragons | 6 – 30 | North Queensland Cowboys | WIN Stadium | View |
| 27 March | Penrith Panthers | 22 – 36 | Melbourne Storm | CUA Stadium | View |
| 27 March | Manly Sea Eagles | 22 – 30 | Newcastle Knights | Bluetongue Stadium | View |
| 27 March | Gold Coast Titans | 12 – 14 | Canberra Raiders | Skilled Park | View |
| 28 March | Brisbane Broncos | 30 – 18 | Warriors | Suncorp Stadium | View |
| 28 March | Canterbury Bulldogs | 40 – 40 | Sydney Roosters | ANZ Stadium | View |
| 29 March | Cronulla Sharks | 22 – 16 | South Sydney Rabbitohs | Toyota Stadium | View |
| Round 4 | |||||
| 2 April | Sydney Roosters | 39 – 36 | Brisbane Broncos | Sydney Football Stadium | View |
| 3 April | Melbourne Storm | 30 – 50 | St George Illawarra Dragons | Olympic Park | View |
| 3 April | Cronulla Sharks | 20 – 14 | Parramatta Eels | Toyota Stadium | View |
| 3 April | North Queensland Cowboys | 48 – 8 | Gold Coast Titans | Dairy Farmers Stadium | View |
| 4 April | Warriors | 12 – 30 | Manly Sea Eagles | Mt Smart Stadium | View |
| 4 April | Canberra Raiders | 34 – 42 | Wests Tigers | Canberra Stadium | View |
| 5 April | Newcastle Knights | 44 – 28 | Penrith Panthers | EnergyAustralia Stadium | View |
| 5 April | South Sydney Rabbitohs | 44 – 6 | Canterbury Bulldogs | ANZ Stadium | View |
| Round 5 | |||||
| 9 April | St George Illawarra Dragons | 14 – 26 | Brisbane Broncos | WIN Stadium | View |
| 9 April | Gold Coast Titans | 22 – 22 | Melbourne Storm | Skilled Park | View |
| 10 April | South Sydney Rabbitohs | 48 – 34 | Newcastle Knights | Bluetongue Stadium | View |
| 10 April | Canterbury Bulldogs | 30 – 36 | Warriors | ANZ Stadium | View |
| 10 April | North Queensland Cowboys | 28 – 38 | Wests Tigers | Dairy Farmers Stadium | View |
| 11 April | Manly Sea Eagles | 30 – 16 | Cronulla Sharks | Brookvale Oval | View |
| 11 April | Penrith Panthers | 12 – 40 | Sydney Roosters | CUA Stadium | View |
| 12 April | Parramatta Eels | 22 – 40 | Canberra Raiders | Parramatta Stadium | View |
| Round 6 | |||||
| 16 April | Wests Tigers | 36 – 16 | Canterbury Bulldogs | Sydney Football Stadium | View |
| 16 April | Gold Coast Titans | 10 – 30 | St George Illawarra Dragons | Skilled Park | View |
| 17 April | Newcastle Knights | 22 – 36 | North Queensland Cowboys | EnergyAustralia Stadium | View |
| 17 April | Sydney Roosters | 24 – 25 | Canberra Raiders | Sydney Football Stadium | View |
| 18 April | Warriors | 56 – 10 | Penrith Panthers | Mt Smart Stadium | View |
| 18 April | Brisbane Broncos | 38 – 18 | Cronulla Sharks | Suncorp Stadium | View |
| 18 April | Parramatta Eels | 22 – 24 | South Sydney Rabbitohs | Parramatta Stadium | View |
| 19 April | Melbourne Storm | 18 – 42 | Manly Sea Eagles | Etihad Stadium | View |
| Round 7 | |||||
| 23 April | Canterbury Bulldogs | 12 – 28 | Brisbane Broncos | ANZ Stadium | View |
| 23 April | North Queensland Cowboys | 50 – 14 | Parramatta Eels | Dairy Farmers Stadium | View |
| 24 April | Penrith Panthers | 16 – 42 | Wests Tigers | CUA Stadium | View |
| 24 April | Cronulla Sharks | 22 – 18 | Newcastle Knights | Toyota Stadium | View |
| 25 April | Canberra Raiders | 20 – 38 | South Sydney Rabbitohs | Canberra Stadium | View |
| 25 April | St George Illawarra Dragons | 22 – 54 | Sydney Roosters | Sydney Football Stadium | View |
| 25 April | Melbourne Storm | 22 – 46 | Warriors | Etihad Stadium | View |
| 26 April | Manly Sea Eagles | 50 – 6 | Gold Coast Titans | Brookvale Oval | View |
| Round 8 | |||||
| 30 April | Parramatta Eels | 14 – 34 | Canterbury Bulldogs | ANZ Stadium | View |
| 30 April | Brisbane Broncos | 58 – 20 | Newcastle Knights | Suncorp Stadium | View |
| 1 May | Warriors | 40 – 36 | Canberra Raiders | Mt Smart Stadium | View |
| 1 May | Gold Coast Titans | 22 – 48 | Penrith Panthers | Skilled Park | View |
| 1 May | North Queensland Cowboys | 34 – 30 | Melbourne Storm | Dairy Farmers Stadium | View |
| 1 May | St George Illawarra Dragons | 10 – 20 | Cronulla Sharks | WIN Stadium | View |
| 2 May | Wests Tigers | 36 – 16 | Sydney Roosters | Campbelltown Stadium | View |
| 2 May | South Sydney Rabbitohs | 30 – 24 | Manly Sea Eagles | ANZ Stadium | View |
| Round 9 | |||||
| 8 May | Manly Sea Eagles | 14 – 22 | St George Illawarra Dragons | Brookvale Oval | View |
| 9 May | Newcastle Knights | 50 – 22 | Gold Coast Titans | EnergyAustralia Stadium | View |
| 9 May | Melbourne Storm | 14 – 40 | Brisbane Broncos | AAMI Park | View |
| 10 May | Sydney Roosters | 32 – 24 | North Queensland Cowboys | Sydney Football Stadium | View |
| Canberra Raiders | BYE | ||||
| Canterbury Bulldogs | BYE | ||||
| Cronulla Sharks | BYE | ||||
| Parramatta Eels | BYE | ||||
| Penrith Panthers | BYE | ||||
| South Sydney Rabbitohs | BYE | ||||
| Warriors | BYE | ||||
| Wests Tigers | BYE |
| Round 10 | |||||
| 14 May | Brisbane Broncos | 28 – 30 | Gold Coast Titans | Suncorp Stadium | View |
| 14 May | Canterbury Bulldogs | 30 – 28 | St George Illawarra Dragons | ANZ Stadium | View |
| 15 May | Warriors | 16 – 24 | North Queensland Cowboys | Mt Smart Stadium | View |
| 15 May | Canberra Raiders | 32 – 30 | Melbourne Storm | Canberra Stadium | View |
| 15 May | Sydney Roosters | 4 – 34 | Newcastle Knights | Bluetongue Stadium | View |
| 16 May | Wests Tigers | 24 – 13 | South Sydney Rabbitohs | Sydney Football Stadium | View |
| 16 May | Cronulla Sharks | 26 – 36 | Penrith Panthers | Toyota Stadium | View |
| 17 May | Manly Sea Eagles | 24 – 18 | Parramatta Eels | Brookvale Oval | View |
| Round 11 | |||||
| 21 May | Newcastle Knights | 22 – 18 | Wests Tigers | EnergyAustralia Stadium | View |
| 22 May | Parramatta Eels | 22 – 24 | Cronulla Sharks | Parramatta Stadium | View |
| 23 May | Warriors | 41 – 18 | South Sydney Rabbitohs | Mt Smart Stadium | View |
| 23 May | St George Illawarra Dragons | 20 – 28 | Canberra Raiders | WIN Stadium | View |
| 24 May | Penrith Panthers | 16 – 40 | Canterbury Bulldogs | CUA Stadium | View |
| Brisbane Broncos | BYE | ||||
| Gold Coast Titans | BYE | ||||
| Manly Sea Eagles | BYE | ||||
| Melbourne Storm | BYE | ||||
| North Queensland Cowboys | BYE | ||||
| Sydney Roosters | BYE |
| Round 12 | |||||
| 28 May | St George Illawarra Dragons | 27 – 16 | Parramatta Eels | WIN Jubilee Oval | View |
| 28 May | Wests Tigers | 18 – 10 | Warriors | Campbelltown Stadium | View |
| 29 May | Cronulla Sharks | 30 – 34 | Brisbane Broncos | Toyota Stadium | View |
| 29 May | North Queensland Cowboys | 16 – 30 | Manly Sea Eagles | Dairy Farmers Stadium | View |
| 30 May | Melbourne Storm | 16 – 46 | Canterbury Bulldogs | AAMI Park | View |
| 30 May | South Sydney Rabbitohs | 38 – 30 | Penrith Panthers | ANZ Stadium | View |
| 31 May | Gold Coast Titans | 34 – 36 | Sydney Roosters | Skilled Park | View |
| Canberra Raiders | BYE | ||||
| Newcastle Knights | BYE |
| Round 13 | |||||
| 4 June | Parramatta Eels | 22 – 29 | Melbourne Storm | Parramatta Stadium | View |
| 5 June | Canterbury Bulldogs | 36 – 30 | Wests Tigers | Terry Lamb Complex | View |
| 5 June | Penrith Panthers | 64 – 32 | Newcastle Knights | CUA Stadium | View |
| 5 June | Sydney Roosters | 24 – 20 | Cronulla Sharks | Sydney Football Stadium | View |
| 5 June | Warriors | 19 – 0 | St George Illawarra Dragons | Mt Smart Stadium | View |
| 6 June | Canberra Raiders | 24 – 52 | Gold Coast Titans | Canberra Stadium | View |
| 7 June | South Sydney Rabbitohs | 25 – 24 | North Queensland Cowboys | ANZ Stadium | View |
| 6 July | Manly Sea Eagles | 30 – 16 | Brisbane Broncos | Brookvale Oval | View |
| Round 14 | |||||
| 11 June | Gold Coast Titans | 34 – 20 | Manly Sea Eagles | Skilled Park | View |
| 12 June | North Queensland Cowboys | 24 – 38 | Canberra Raiders | Dairy Farmers Stadium | View |
| 13 June | Newcastle Knights | 38 – 10 | Warriors | EnergyAustralia Stadium | View |
| 13 June | Brisbane Broncos | 28 – 36 | South Sydney Rabbitohs | Suncorp Stadium | View |
| 14 June | Melbourne Storm | 12 – 60 | Sydney Roosters | AAMI Park | View |
| Canterbury Bulldogs | BYE | ||||
| Cronulla Sharks | BYE | ||||
| Parramatta Eels | BYE | ||||
| Penrith Panthers | BYE | ||||
| St George Illawarra Dragons | BYE | ||||
| Wests Tigers | BYE |
| Round 15 | |||||
| 18 June | Brisbane Broncos | 20 – 28 | Penrith Panthers | Suncorp Stadium | View |
| 19 June | Canterbury Bulldogs | 28 – 34 | Gold Coast Titans | North Sydney Oval | View |
| 19 June | Melbourne Storm | 28 – 28 | North Queensland Cowboys | AAMI Park | View |
| 19 June | Manly Sea Eagles | 16 – 36 | South Sydney Rabbitohs | Brookvale Oval | View |
| 20 June | Cronulla Sharks | 6 – 42 | St George Illawarra Dragons | Toyota Stadium | View |
| 20 June | Wests Tigers | 26 – 42 | Canberra Raiders | Leichhardt Oval | View |
| 21 June | Newcastle Knights | 34 – 20 | Parramatta Eels | EnergyAustralia Stadium | View |
| Sydney Roosters | BYE | ||||
| Warriors | BYE |
| Round 16 | |||||
| 25 June | St George Illawarra Dragons | 31 – 10 | Wests Tigers | WIN Jubilee Oval | View |
| 25 June | Penrith Panthers | 30 – 26 | Manly Sea Eagles | CUA Stadium | View |
| 26 June | Parramatta Eels | 26 – 20 | Brisbane Broncos | Parramatta Stadium | View |
| 26 June | North Queensland Cowboys | 20 – 8 | Cronulla Sharks | Dairy Farmers Stadium | View |
| 27 June | South Sydney Rabbitohs | 48 – 28 | Melbourne Storm | North Sydney Oval | View |
| 27 June | Sydney Roosters | 10 – 18 | Warriors | AMI Stadium | View |
| 27 June | Gold Coast Titans | 21 – 20 | Newcastle Knights | Skilled Park | View |
| 28 June | Canberra Raiders | 26 – 30 | Canterbury Bulldogs | Canberra Stadium | View |
| Round 17 | |||||
| 2 July | Brisbane Broncos | 16 – 20 | Wests Tigers | Suncorp Stadium | View |
| 3 July | Cronulla Sharks | 16 – 34 | Canterbury Bulldogs | Bluetongue Stadium | View |
| 4 July | Canberra Raiders | 18 – 28 | Sydney Roosters | Canberra Stadium | View |
| 4 July | Warriors | 40 – 6 | Parramatta Eels | Mt Smart Stadium | View |
| 5 July | St George Illawarra Dragons | 6 – 34 | Penrith Panthers | WIN Jubilee Oval | View |
| Gold Coast Titans | BYE | ||||
| Manly Sea Eagles | BYE | ||||
| Melbourne Storm | BYE | ||||
| Newcastle Knights | BYE | ||||
| North Queensland Cowboys | BYE | ||||
| South Sydney Rabbitohs | BYE |
| Round 18 | |||||
| 9 July | Wests Tigers | 18 – 24 | Gold Coast Titans | Campbelltown Stadium | View |
| 9 July | Sydney Roosters | 14 – 12 | South Sydney Rabbitohs | Sydney Football Stadium | View |
| 10 July | Canterbury Bulldogs | 42 – 20 | Melbourne Storm | The Crest Stadium | View |
| 10 July | Manly Sea Eagles | 12 – 20 | Canberra Raiders | Brookvale Oval | View |
| 11 July | Newcastle Knights | 12 – 14 | Cronulla Sharks | EnergyAustralia Stadium | View |
| 11 July | Penrith Panthers | 10 – 38 | Warriors | CUA Stadium | View |
| 11 July | Parramatta Eels | 26 – 26 | North Queensland Cowboys | Ringrose Park | View |
| Brisbane Broncos | BYE | ||||
| St George Illawarra Dragons | BYE |
| Round 19 | |||||
| 16 July | Gold Coast Titans | 36 – 30 | Brisbane Broncos | Skilled Park | View |
| 16 July | South Sydney Rabbitohs | 16 – 12 | St George Illawarra Dragons | ANZ Stadium | View |
| 17 July | Warriors | 24 – 12 | Melbourne Storm | Mt Smart Stadium | View |
| 17 July | Penrith Panthers | 18 – 30 | Parramatta Eels | CUA Stadium | View |
| 17 July | Cronulla Sharks | 14 – 22 | Manly Sea Eagles | Toyota Stadium | View |
| 18 July | Canberra Raiders | 29 – 22 | Newcastle Knights | Canberra Stadium | View |
| 18 July | Sydney Roosters | 28 – 38 | Canterbury Bulldogs | Sydney Football Stadium | View |
| 19 July | Wests Tigers | 20 – 28 | North Queensland Cowboys | Leichhardt Oval | View |
| Round 20 | |||||
| 23 July | Canterbury Bulldogs | 30 – 28 | Parramatta Eels | ANZ Stadium | View |
| 23 July | St George Illawarra Dragons | 34 – 12 | Gold Coast Titans | WIN Jubilee Oval | View |
| 24 July | Canberra Raiders | 48 – 28 | Cronulla Sharks | Canberra Stadium | View |
| 24 July | Melbourne Storm | 46 – 16 | Penrith Panthers | AAMI Park | View |
| 24 July | North Queensland Cowboys | 38 – 14 | Newcastle Knights | Dairy Farmers Stadium | View |
| 25 July | South Sydney Rabbitohs | 18 – 19 | Warriors | ANZ Stadium | View |
| 25 July | Manly Sea Eagles | 24 – 20 | Wests Tigers | Bluetongue Stadium | View |
| 26 July | Brisbane Broncos | 22 – 36 | Sydney Roosters | Suncorp Stadium | View |
| Round 21 | |||||
| 30 July | Canterbury Bulldogs | 25 – 12 | South Sydney Rabbitohs | ANZ Stadium | View |
| 30 July | Penrith Panthers | 18 – 38 | North Queensland Cowboys | CUA Stadium | View |
| 31 July | Parramatta Eels | 26 – 28 | Sydney Roosters | Parramatta Stadium | View |
| 31 July | Wests Tigers | 14 – 10 | Cronulla Sharks | Leichhardt Oval | View |
| 1 August | Warriors | 30 – 14 | Gold Coast Titans | Mt Smart Stadium | View |
| 1 August | Melbourne Storm | 22 – 50 | Canberra Raiders | AAMI Park | View |
| 1 August | Brisbane Broncos | 20 – 18 | St George Illawarra Dragons | Suncorp Stadium | View |
| 2 August | Newcastle Knights | 25 – 10 | Manly Sea Eagles | EnergyAustralia Stadium | View |
| Round 22 | |||||
| 6 August | North Queensland Cowboys | 20 – 20 | Brisbane Broncos | Dairy Farmers Stadium | View |
| 6 August | Gold Coast Titans | 46 – 0 | Parramatta Eels | Skilled Park | View |
| 7 August | Manly Sea Eagles | 32 – 30 | Melbourne Storm | Brookvale Oval | View |
| 7 August | South Sydney Rabbitohs | 16 – 14 | Wests Tigers | ANZ Stadium | View |
| 7 August | Cronulla Sharks | 31 – 24 | Warriors | Toyota Stadium | View |
| 8 August | Newcastle Knights | 26 – 26 | Canterbury Bulldogs | EnergyAustralia Stadium | View |
| 8 August | Sydney Roosters | 39 – 26 | St George Illawarra Dragons | Sydney Cricket Ground | View |
| 9 August | Canberra Raiders | 44 – 34 | Penrith Panthers | Canberra Stadium | View |
| Round 23 | |||||
| 13 August | Brisbane Broncos | 46 – 18 | Parramatta Eels | Suncorp Stadium | View |
| 13 August | Cronulla Sharks | 20 – 16 | Sydney Roosters | Toyota Stadium | View |
| 14 August | Gold Coast Titans | 22 – 24 | North Queensland Cowboys | Skilled Park | View |
| 14 August | Canterbury Bulldogs | 60 – 18 | Canberra Raiders | ANZ Stadium | View |
| 15 August | Warriors | 28 – 26 | Newcastle Knights | Mt Smart Stadium | View |
| 15 August | Melbourne Storm | 42 – 46 | South Sydney Rabbitohs | AAMI Park | View |
| 15 August | Wests Tigers | 44 – 24 | Penrith Panthers | Campbelltown Stadium | View |
| 16 August | St George Illawarra Dragons | 46 – 14 | Manly Sea Eagles | WIN Jubilee Oval | View |
| Round 24 | |||||
| 20 August | Penrith Panthers | 24 – 26 | South Sydney Rabbitohs | CUA Stadium | View |
| 20 August | Newcastle Knights | 22 – 38 | Brisbane Broncos | EnergyAustralia Stadium | View |
| 21 August | Manly Sea Eagles | 18 – 56 | Warriors | Brookvale Oval | View |
| 21 August | North Queensland Cowboys | 10 – 50 | Canterbury Bulldogs | Dairy Farmers Stadium | View |
| 21 August | Melbourne Storm | 32 – 22 | Cronulla Sharks | AAMI Park | View |
| 22 August | Canberra Raiders | 28 – 28 | St George Illawarra Dragons | Canberra Stadium | View |
| 22 August | Parramatta Eels | 12 – 34 | Wests Tigers | Parramatta Stadium | View |
| 23 August | Sydney Roosters | 28 – 14 | Gold Coast Titans | Sydney Football Stadium | View |
| Round 25 | |||||
| 27 August | Warriors | 42 – 12 | Brisbane Broncos | Mt Smart Stadium | View |
| 27 August | South Sydney Rabbitohs | 34 – 28 | Parramatta Eels | ANZ Stadium | View |
| 28 August | Cronulla Sharks | 21 – 28 | Gold Coast Titans | Toyota Stadium | View |
| 28 August | Newcastle Knights | 6 – 44 | St George Illawarra Dragons | EnergyAustralia Stadium | View |
| 28 August | Canberra Raiders | 30 – 22 | North Queensland Cowboys | Canberra Stadium | View |
| 29 August | Wests Tigers | 10 – 20 | Melbourne Storm | Leichhardt Oval | View |
| 29 August | Sydney Roosters | 19 – 20 | Manly Sea Eagles | Sydney Football Stadium | View |
| 30 August | Canterbury Bulldogs | 48 – 40 | Penrith Panthers | ANZ Stadium | View |
| Round 26 | |||||
| 3 September | Brisbane Broncos | 40 – 36 | Canberra Raiders | Suncorp Stadium | View |
| 3 September | Gold Coast Titans | 24 – 18 | Wests Tigers | Skilled Park | View |
| 4 September | Parramatta Eels | 6 – 52 | Warriors | Parramatta Stadium | View |
| 4 September | Penrith Panthers | 34 – 32 | Cronulla Sharks | CUA Stadium | View |
| 4 September | North Queensland Cowboys | 29 – 28 | Sydney Roosters | Dairy Farmers Stadium | View |
| 5 September | Melbourne Storm | 46 – 16 | Newcastle Knights | AAMI Park | View |
| 5 September | Manly Sea Eagles | 6 – 38 | Canterbury Bulldogs | Brookvale Oval | View |
| 5 September | St George Illawarra Dragons | 22 – 47 | South Sydney Rabbitohs | WIN Jubilee Oval | View |