| Round 1 | |||||
| 11 March | Sydney Roosters | 28 – 32 | South Sydney Rabbitohs | Sydney Football Stadium | View |
| 11 March | Brisbane Broncos | 46 – 24 | North Queensland Cowboys | Suncorp Stadium | View |
| 12 March | Warriors | 20 – 16 | Parramatta Eels | Eden Park | View |
| 12 March | Gold Coast Titans | 4 – 38 | St George Illawarra Dragons | Skilled Park | View |
| 12 March | Melbourne Storm | 40 – 12 | Manly Sea Eagles | AAMI Park | View |
| 13 March | Canberra Raiders | 30 – 34 | Cronulla Sharks | Canberra Stadium | View |
| 13 March | Penrith Panthers | 16 – 62 | Newcastle Knights | Centrebet Stadium | View |
| 14 March | Canterbury Bulldogs | 16 – 6 | Wests Tigers | ANZ Stadium | View |
| Round 2 | |||||
| 18 March | Parramatta Eels | 16 – 26 | Penrith Panthers | Parramatta Stadium | View |
| 18 March | Canberra Raiders | 38 – 22 | Brisbane Broncos | Canberra Stadium | View |
| 19 March | Melbourne Storm | 44 – 10 | Gold Coast Titans | AAMI Park | View |
| 19 March | Wests Tigers | 36 – 22 | Warriors | Leichhardt Oval | View |
| 19 March | North Queensland Cowboys | 24 – 20 | Newcastle Knights | Dairy Farmers Stadium | View |
| 20 March | South Sydney Rabbitohs | 22 – 33 | Canterbury Bulldogs | ANZ Stadium | View |
| 20 March | Sydney Roosters | 32 – 16 | Manly Sea Eagles | Sydney Football Stadium | View |
| 21 March | Cronulla Sharks | 38 – 12 | St George Illawarra Dragons | Toyota Stadium | View |
| Round 3 | |||||
| 25 March | Parramatta Eels | 43 – 18 | South Sydney Rabbitohs | Parramatta Stadium | View |
| 25 March | Gold Coast Titans | 14 – 46 | Brisbane Broncos | Skilled Park | View |
| 26 March | Penrith Panthers | 36 – 32 | Cronulla Sharks | Centrebet Stadium | View |
| 26 March | Wests Tigers | 18 – 40 | Canberra Raiders | Campbelltown Stadium | View |
| 27 March | Warriors | 54 – 24 | St George Illawarra Dragons | Mt Smart Stadium | View |
| 27 March | Canterbury Bulldogs | 20 – 22 | Sydney Roosters | ANZ Stadium | View |
| 27 March | Manly Sea Eagles | 20 – 24 | Newcastle Knights | Brookvale Oval | View |
| 28 March | North Queensland Cowboys | 36 – 12 | Melbourne Storm | Dairy Farmers Stadium | View |
| Round 4 | |||||
| 1 April | South Sydney Rabbitohs | 28 – 36 | Manly Sea Eagles | Bluetongue Stadium | View |
| 1 April | Brisbane Broncos | 28 – 18 | Penrith Panthers | Suncorp Stadium | View |
| 2 April | Canberra Raiders | 58 – 18 | Gold Coast Titans | Canberra Stadium | View |
| 2 April | Parramatta Eels | 28 – 34 | North Queensland Cowboys | Parramatta Stadium | View |
| 3 April | Cronulla Sharks | 16 – 40 | Warriors | Owen Delany Park | View |
| 3 April | Newcastle Knights | 28 – 14 | St George Illawarra Dragons | Ausgrid Stadium | View |
| 3 April | Sydney Roosters | 22 – 22 | Wests Tigers | Sydney Football Stadium | View |
| 4 April | Melbourne Storm | 34 – 30 | Canterbury Bulldogs | AAMI Park | View |
| Round 5 | |||||
| 8 April | Wests Tigers | 22 – 24 | South Sydney Rabbitohs | Sydney Football Stadium | View |
| 8 April | North Queensland Cowboys | 36 – 12 | Gold Coast Titans | Skilled Park | View |
| 9 April | Warriors | 42 – 0 | Sydney Roosters | Mt Smart Stadium | View |
| 9 April | Cronulla Sharks | 21 – 20 | Manly Sea Eagles | Toyota Stadium | View |
| 9 April | Penrith Panthers | 12 – 44 | Canberra Raiders | Centrebet Stadium | View |
| 10 April | Melbourne Storm | 22 – 16 | Parramatta Eels | AAMI Park | View |
| 10 April | St George Illawarra Dragons | 8 – 46 | Canterbury Bulldogs | WIN Jubilee Oval | View |
| 11 April | Brisbane Broncos | 54 – 6 | Newcastle Knights | Suncorp Stadium | View |
| Round 6 | |||||
| 15 April | Parramatta Eels | 28 – 26 | Canterbury Bulldogs | ANZ Stadium | View |
| 15 April | Gold Coast Titans | 14 – 14 | Wests Tigers | Skilled Park | View |
| 16 April | Manly Sea Eagles | 18 – 30 | Warriors | Brookvale Oval | View |
| 16 April | Sydney Roosters | 8 – 32 | Brisbane Broncos | Bluetongue Stadium | View |
| 16 April | North Queensland Cowboys | 42 – 12 | Canberra Raiders | Dairy Farmers Stadium | View |
| 17 April | Newcastle Knights | 30 – 42 | Cronulla Sharks | Ausgrid Stadium | View |
| 17 April | Penrith Panthers | 24 – 26 | Melbourne Storm | Centrebet Stadium | View |
| 18 April | South Sydney Rabbitohs | 22 – 22 | St George Illawarra Dragons | ANZ Stadium | View |
| Round 7 | |||||
| 22 April | Manly Sea Eagles | 24 – 38 | Penrith Panthers | Brookvale Oval | View |
| 22 April | Wests Tigers | 30 – 16 | Brisbane Broncos | Sydney Football Stadium | View |
| 23 April | Cronulla Sharks | 36 – 20 | North Queensland Cowboys | Toyota Stadium | View |
| 23 April | Canterbury Bulldogs | 38 – 16 | South Sydney Rabbitohs | ANZ Stadium | View |
| 24 April | Canberra Raiders | 34 – 24 | Newcastle Knights | Canberra Stadium | View |
| 24 April | Parramatta Eels | 18 – 16 | Gold Coast Titans | Parramatta Stadium | View |
| 25 April | Sydney Roosters | 16 – 18 | St George Illawarra Dragons | Sydney Football Stadium | View |
| 25 April | Melbourne Storm | 40 – 10 | Warriors | AAMI Park | View |
| Round 8 | |||||
| 29 April | Brisbane Broncos | 6 – 24 | Canterbury Bulldogs | Suncorp Stadium | View |
| 29 April | South Sydney Rabbitohs | 16 – 46 | Cronulla Sharks | ANZ Stadium | View |
| 30 April | Gold Coast Titans | 10 – 30 | Sydney Roosters | Skilled Park | View |
| 30 April | Melbourne Storm | 46 – 12 | Newcastle Knights | AAMI Park | View |
| 30 April | North Queensland Cowboys | 38 – 10 | Manly Sea Eagles | Dairy Farmers Stadium | View |
| 1 May | Warriors | 56 – 26 | Penrith Panthers | Mt Smart Stadium | View |
| 1 May | Canberra Raiders | 31 – 37 | Wests Tigers | Canberra Stadium | View |
| 1 May | St George Illawarra Dragons | 24 – 10 | Parramatta Eels | WIN Jubilee Oval | View |
| Round 9 | |||||
| 7 May | Brisbane Broncos | 24 – 38 | Melbourne Storm | Suncorp Stadium | View |
| 8 May | Gold Coast Titans | 20 – 38 | Warriors | Skilled Park | View |
| 8 May | St George Illawarra Dragons | 6 – 34 | North Queensland Cowboys | WIN Jubilee Oval | View |
| 9 May | Manly Sea Eagles | 20 – 58 | Canberra Raiders | Brookvale Oval | View |
| Canterbury Bulldogs | BYE | ||||
| Cronulla Sharks | BYE | ||||
| Newcastle Knights | BYE | ||||
| Parramatta Eels | BYE | ||||
| Penrith Panthers | BYE | ||||
| South Sydney Rabbitohs | BYE | ||||
| Sydney Roosters | BYE | ||||
| Wests Tigers | BYE |
| Round 10 | |||||
| 13 May | Brisbane Broncos | 10 – 44 | Penrith Panthers | Centrebet Stadium | View |
| 13 May | Canterbury Bulldogs | 16 – 14 | St George Illawarra Dragons | ANZ Stadium | View |
| 14 May | Melbourne Storm | 24 – 12 | Canberra Raiders | AAMI Park | View |
| 14 May | South Sydney Rabbitohs | 14 – 38 | Wests Tigers | ANZ Stadium | View |
| 14 May | North Queensland Cowboys | 16 – 29 | Parramatta Eels | Dairy Farmers Stadium | View |
| 15 May | Newcastle Knights | 28 – 48 | Warriors | Ausgrid Stadium | View |
| 15 May | Cronulla Sharks | 19 – 28 | Sydney Roosters | Toyota Stadium | View |
| 16 May | Gold Coast Titans | 34 – 32 | Manly Sea Eagles | Skilled Park | View |
| Round 11 | |||||
| 20 May | Canberra Raiders | 10 – 38 | Canterbury Bulldogs | Canberra Stadium | View |
| 21 May | Wests Tigers | 44 – 16 | Penrith Panthers | Campbelltown Stadium | View |
| 22 May | Warriors | 62 – 6 | South Sydney Rabbitohs | Mt Smart Stadium | View |
| 22 May | Sydney Roosters | 18 – 50 | Newcastle Knights | Sydney Football Stadium | View |
| 23 May | Parramatta Eels | 36 – 36 | Cronulla Sharks | Parramatta Stadium | View |
| Brisbane Broncos | BYE | ||||
| Gold Coast Titans | BYE | ||||
| Manly Sea Eagles | BYE | ||||
| Melbourne Storm | BYE | ||||
| North Queensland Cowboys | BYE | ||||
| St George Illawarra Dragons | BYE |
| Round 12 | |||||
| 27 May | Manly Sea Eagles | 36 – 26 | Brisbane Broncos | Suncorp Stadium | View |
| 28 May | Canterbury Bulldogs | 26 – 24 | Gold Coast Titans | The Crest Stadium | View |
| 28 May | Newcastle Knights | 8 – 28 | Parramatta Eels | Ausgrid Stadium | View |
| 28 May | North Queensland Cowboys | 22 – 20 | Sydney Roosters | Dairy Farmers Stadium | View |
| 29 May | Melbourne Storm | 28 – 42 | Cronulla Sharks | AAMI Park | View |
| 29 May | St George Illawarra Dragons | 22 – 34 | Wests Tigers | WIN Jubilee Oval | View |
| 30 May | Penrith Panthers | 18 – 16 | South Sydney Rabbitohs | Centrebet Stadium | View |
| Canberra Raiders | BYE | ||||
| Warriors | BYE |
| Round 13 | |||||
| 3 June | Cronulla Sharks | 22 – 18 | Brisbane Broncos | Toyota Stadium | View |
| 3 June | Parramatta Eels | 16 – 10 | St George Illawarra Dragons | Parramatta Stadium | View |
| 4 June | Gold Coast Titans | 11 – 10 | Penrith Panthers | Skilled Park | View |
| 4 June | Canterbury Bulldogs | 50 – 6 | Manly Sea Eagles | ANZ Stadium | View |
| 4 June | Sydney Roosters | 10 – 50 | Warriors | Sydney Football Stadium | View |
| 5 June | Canberra Raiders | 18 – 20 | North Queensland Cowboys | Canberra Stadium | View |
| 5 June | South Sydney Rabbitohs | 16 – 40 | Melbourne Storm | ANZ Stadium | View |
| 6 June | Wests Tigers | 18 – 26 | Newcastle Knights | Leichhardt Oval | View |
| Round 14 | |||||
| 10 June | St George Illawarra Dragons | 36 – 28 | Gold Coast Titans | WIN Jubilee Oval | View |
| 11 June | Manly Sea Eagles | 22 – 20 | North Queensland Cowboys | Brookvale Oval | View |
| 12 June | Brisbane Broncos | 34 – 34 | Canberra Raiders | Suncorp Stadium | View |
| 12 June | Warriors | 30 – 16 | Wests Tigers | Mt Smart Stadium | View |
| 15 June | Melbourne Storm | 28 – 20 | Sydney Roosters | Olympic Park | View |
| Canterbury Bulldogs | BYE | ||||
| Cronulla Sharks | BYE | ||||
| Newcastle Knights | BYE | ||||
| Parramatta Eels | BYE | ||||
| Penrith Panthers | BYE | ||||
| South Sydney Rabbitohs | BYE |
| Round 15 | |||||
| 17 June | Brisbane Broncos | 18 – 22 | St George Illawarra Dragons | Suncorp Stadium | View |
| 18 June | South Sydney Rabbitohs | 28 – 24 | Gold Coast Titans | Redfern Oval | View |
| 18 June | Newcastle Knights | 28 – 10 | Penrith Panthers | Ausgrid Stadium | View |
| 18 June | North Queensland Cowboys | 42 – 22 | Warriors | Dairy Farmers Stadium | View |
| 19 June | Canterbury Bulldogs | 30 – 26 | Cronulla Sharks | ANZ Stadium | View |
| 19 June | Wests Tigers | 60 – 20 | Melbourne Storm | Leichhardt Oval | View |
| 20 June | Manly Sea Eagles | 16 – 30 | Parramatta Eels | Brookvale Oval | View |
| Canberra Raiders | BYE | ||||
| Sydney Roosters | BYE |
| Round 16 | |||||
| 24 June | Wests Tigers | 22 – 18 | Canterbury Bulldogs | Campbelltown Stadium | View |
| 25 June | Gold Coast Titans | 16 – 28 | Cronulla Sharks | Skilled Park | View |
| 25 June | Canberra Raiders | 40 – 30 | Parramatta Eels | Canberra Stadium | View |
| 26 June | Warriors | 34 – 16 | Melbourne Storm | Mt Smart Stadium | View |
| 26 June | Penrith Panthers | 10 – 46 | North Queensland Cowboys | Centrebet Stadium | View |
| 26 June | Newcastle Knights | 14 – 26 | Sydney Roosters | Ausgrid Stadium | View |
| 26 June | South Sydney Rabbitohs | 24 – 32 | Brisbane Broncos | North Sydney Oval | View |
| 27 June | Manly Sea Eagles | 42 – 24 | St George Illawarra Dragons | WIN Stadium | View |
| Round 17 | |||||
| 1 July | Parramatta Eels | 46 – 16 | Brisbane Broncos | Parramatta Stadium | View |
| 2 July | Penrith Panthers | 22 – 20 | Canterbury Bulldogs | Centrebet Stadium | View |
| 3 July | Cronulla Sharks | 16 – 6 | South Sydney Rabbitohs | Toyota Stadium | View |
| 3 July | St George Illawarra Dragons | 28 – 28 | Newcastle Knights | WIN Stadium | View |
| 4 July | Sydney Roosters | 56 – 20 | Canberra Raiders | Sydney Football Stadium | View |
| Gold Coast Titans | BYE | ||||
| Manly Sea Eagles | BYE | ||||
| Melbourne Storm | BYE | ||||
| North Queensland Cowboys | BYE | ||||
| Warriors | BYE | ||||
| Wests Tigers | BYE |
| Round 18 | |||||
| 8 July | Parramatta Eels | 4 – 24 | Wests Tigers | Parramatta Stadium | View |
| 8 July | Warriors | 31 – 18 | Gold Coast Titans | Mt Smart Stadium | View |
| 9 July | Canterbury Bulldogs | 24 – 30 | Melbourne Storm | The Crest Stadium | View |
| 9 July | Cronulla Sharks | 34 – 24 | Canberra Raiders | Toyota Stadium | View |
| 10 July | Sydney Roosters | 42 – 28 | Penrith Panthers | Sydney Football Stadium | View |
| 10 July | Manly Sea Eagles | 30 – 52 | South Sydney Rabbitohs | Brookvale Oval | View |
| 11 July | Newcastle Knights | 26 – 50 | North Queensland Cowboys | Ausgrid Stadium | View |
| Brisbane Broncos | BYE | ||||
| St George Illawarra Dragons | BYE |
| Round 19 | |||||
| 15 July | Brisbane Broncos | 32 – 16 | Gold Coast Titans | Suncorp Stadium | View |
| 15 July | Warriors | 22 – 14 | Canterbury Bulldogs | Mt Smart Stadium | View |
| 16 July | South Sydney Rabbitohs | 16 – 17 | Sydney Roosters | ANZ Stadium | View |
| 16 July | Penrith Panthers | 24 – 16 | Parramatta Eels | Centrebet Stadium | View |
| 16 July | North Queensland Cowboys | 32 – 18 | Wests Tigers | Dairy Farmers Stadium | View |
| 17 July | Canberra Raiders | 10 – 32 | Melbourne Storm | Canberra Stadium | View |
| 17 July | Newcastle Knights | 44 – 12 | Manly Sea Eagles | Ausgrid Stadium | View |
| 18 July | St George Illawarra Dragons | 4 – 38 | Cronulla Sharks | WIN Jubilee Oval | View |
| Round 20 | |||||
| 22 July | Melbourne Storm | 30 – 16 | Brisbane Broncos | AAMI Park | View |
| 23 July | Wests Tigers | 10 – 30 | Sydney Roosters | Campbelltown Stadium | View |
| 23 July | North Queensland Cowboys | 30 – 20 | Gold Coast Titans | Skilled Park | View |
| 23 July | Cronulla Sharks | 38 – 10 | Newcastle Knights | Toyota Stadium | View |
| 24 July | Canterbury Bulldogs | 16 – 12 | Parramatta Eels | Ringrose Park | View |
| 24 July | South Sydney Rabbitohs | 18 – 38 | Warriors | ANZ Stadium | View |
| 24 July | Penrith Panthers | 50 – 16 | Manly Sea Eagles | Centrebet Stadium | View |
| 25 July | Canberra Raiders | 12 – 50 | St George Illawarra Dragons | Canberra Stadium | View |
| Round 21 | |||||
| 29 July | Manly Sea Eagles | 18 – 30 | Wests Tigers | Bluetongue Stadium | View |
| 29 July | Brisbane Broncos | 34 – 35 | Cronulla Sharks | Suncorp Stadium | View |
| 30 July | Sydney Roosters | 50 – 8 | Canterbury Bulldogs | Sydney Football Stadium | View |
| 30 July | North Queensland Cowboys | 44 – 12 | Penrith Panthers | Dairy Farmers Stadium | View |
| 31 July | Warriors | 50 – 14 | Canberra Raiders | Mt Smart Stadium | View |
| 31 July | Newcastle Knights | 52 – 32 | Gold Coast Titans | Ausgrid Stadium | View |
| 31 July | St George Illawarra Dragons | 52 – 18 | South Sydney Rabbitohs | WIN Stadium | View |
| 1 August | Parramatta Eels | 23 – 22 | Melbourne Storm | Parramatta Stadium | View |
| Round 22 | |||||
| 5 August | Wests Tigers | 0 – 28 | St George Illawarra Dragons | Sydney Football Stadium | View |
| 5 August | Canterbury Bulldogs | 18 – 22 | North Queensland Cowboys | ANZ Stadium | View |
| 6 August | Melbourne Storm | 18 – 22 | Penrith Panthers | AAMI Park | View |
| 6 August | Cronulla Sharks | 38 – 18 | Gold Coast Titans | Toyota Stadium | View |
| 6 August | Brisbane Broncos | 26 – 26 | Warriors | Suncorp Stadium | View |
| 7 August | Newcastle Knights | 24 – 8 | Canberra Raiders | Ausgrid Stadium | View |
| 7 August | Manly Sea Eagles | 18 – 26 | Sydney Roosters | Brookvale Oval | View |
| 8 August | South Sydney Rabbitohs | 16 – 42 | Parramatta Eels | ANZ Stadium | View |
| Round 23 | |||||
| 12 August | North Queensland Cowboys | 16 – 42 | Brisbane Broncos | Dairy Farmers Stadium | View |
| 12 August | Penrith Panthers | 26 – 6 | Wests Tigers | Centrebet Stadium | View |
| 13 August | Warriors | 44 – 8 | Newcastle Knights | Mt Smart Stadium | View |
| 13 August | Parramatta Eels | 16 – 26 | Manly Sea Eagles | Parramatta Stadium | View |
| 13 August | Gold Coast Titans | 20 – 22 | Melbourne Storm | Skilled Park | View |
| 14 August | Canberra Raiders | 46 – 14 | South Sydney Rabbitohs | Canberra Stadium | View |
| 14 August | St George Illawarra Dragons | 18 – 26 | Sydney Roosters | WIN Stadium | View |
| 15 August | Cronulla Sharks | 16 – 48 | Canterbury Bulldogs | Toyota Stadium | View |
| Round 24 | |||||
| 19 August | Melbourne Storm | 12 – 16 | St George Illawarra Dragons | AAMI Park | View |
| 19 August | South Sydney Rabbitohs | 10 – 58 | North Queensland Cowboys | ANZ Stadium | View |
| 20 August | Gold Coast Titans | 36 – 28 | Canberra Raiders | Skilled Park | View |
| 20 August | Sydney Roosters | 44 – 6 | Cronulla Sharks | Sydney Football Stadium | View |
| 20 August | Penrith Panthers | 32 – 12 | Warriors | Centrebet Stadium | View |
| 21 August | Manly Sea Eagles | 0 – 52 | Canterbury Bulldogs | Brookvale Oval | View |
| 21 August | Wests Tigers | 36 – 16 | Parramatta Eels | Leichhardt Oval | View |
| 22 August | Newcastle Knights | 28 – 24 | Brisbane Broncos | Ausgrid Stadium | View |
| Round 25 | |||||
| 26 August | Manly Sea Eagles | 0 – 40 | Melbourne Storm | Brookvale Oval | View |
| 26 August | Parramatta Eels | 10 – 40 | Sydney Roosters | Parramatta Stadium | View |
| 27 August | Canterbury Bulldogs | 10 – 12 | Newcastle Knights | ANZ Stadium | View |
| 27 August | North Queensland Cowboys | 42 – 22 | Cronulla Sharks | Dairy Farmers Stadium | View |
| 27 August | Canberra Raiders | 34 – 42 | Penrith Panthers | Canberra Stadium | View |
| 28 August | St George Illawarra Dragons | 30 – 42 | Warriors | WIN Stadium | View |
| 28 August | Brisbane Broncos | 54 – 6 | South Sydney Rabbitohs | Suncorp Stadium | View |
| 29 August | Wests Tigers | 56 – 18 | Gold Coast Titans | Campbelltown Stadium | View |
| Round 26 | |||||
| 2 September | St George Illawarra Dragons | 24 – 30 | Penrith Panthers | WIN Stadium | View |
| 2 September | Newcastle Knights | 46 – 16 | South Sydney Rabbitohs | Ausgrid Stadium | View |
| 3 September | Warriors | 28 – 20 | North Queensland Cowboys | Mt Smart Stadium | View |
| 3 September | Cronulla Sharks | 26 – 10 | Wests Tigers | Toyota Stadium | View |
| 3 September | Gold Coast Titans | 24 – 18 | Parramatta Eels | Skilled Park | View |
| 4 September | Canterbury Bulldogs | 38 – 28 | Canberra Raiders | ANZ Stadium | View |
| 4 September | Brisbane Broncos | 62 – 0 | Manly Sea Eagles | Suncorp Stadium | View |
| 4 September | Sydney Roosters | 28 – 14 | Melbourne Storm | Sydney Football Stadium | View |