| Round 5 | |||||
| 1 April | Penrith Panthers | v | Canberra Raiders | BlueBet Stadium | View |
| 1 April | St George Illawarra Dragons | v | Parramatta Eels | Ziems Park | View |
| 2 April | Manly Sea Eagles | v | Newcastle Knights | HE Laybutt Sporting Complex | View |
| 2 April | Sydney Roosters | v | Melbourne Storm | Wentworth Park | View |
| 2 April | Cronulla Sharks | v | Canterbury Bulldogs | PointsBet Stadium | View |
South Sydney Rabbitohs, Wests Tigers – BYE