| Round 1 | |||||
| 1 March | Newcastle Knights | 44 – 12 | St George Illawarra Dragons | Hunter Stadium | View |
| 2 March | Parramatta Eels | 24 – 16 | Brisbane Broncos | Parramatta Stadium | View |
| 3 March | Canberra Raiders | 16 – 10 | Melbourne Storm | Canberra Stadium | View |
| 3 March | Penrith Panthers | 19 – 12 | Canterbury Bulldogs | Centrebet Stadium | View |
| 3 March | North Queensland Cowboys | 34 – 26 | Gold Coast Titans | Dairy Farmers Stadium | View |
| 4 March | Warriors | 30 – 16 | Manly Sea Eagles | Eden Park | View |
| 4 March | Wests Tigers | 26 – 28 | Cronulla Sharks | Leichhardt Oval | View |
| 5 March | South Sydney Rabbitohs | 34 – 26 | Sydney Roosters | ANZ Stadium | View |
| Round 2 | |||||
| 9 March | Manly Sea Eagles | 22 – 50 | Wests Tigers | Bluetongue Stadium | View |
| 9 March | Brisbane Broncos | 26 – 20 | North Queensland Cowboys | Suncorp Stadium | View |
| 10 March | Gold Coast Titans | 24 – 40 | Canberra Raiders | Skilled Park | View |
| 10 March | Canterbury Bulldogs | 32 – 24 | St George Illawarra Dragons | ANZ Stadium | View |
| 11 March | Cronulla Sharks | 0 – 40 | Newcastle Knights | Toyota Stadium | View |
| 11 March | Sydney Roosters | 26 – 14 | Penrith Panthers | Allianz Stadium | View |
| 11 March | Melbourne Storm | 36 – 10 | South Sydney Rabbitohs | AAMI Park | View |
| 12 March | Parramatta Eels | 28 – 38 | Warriors | Parramatta Stadium | View |
| Round 3 | |||||
| 16 March | St George Illawarra Dragons | 10 – 28 | Wests Tigers | WIN Jubilee Oval | View |
| 16 March | Newcastle Knights | 16 – 24 | Brisbane Broncos | Hunter Stadium | View |
| 17 March | Gold Coast Titans | 26 – 27 | Melbourne Storm | Skilled Park | View |
| 17 March | North Queensland Cowboys | 22 – 30 | Parramatta Eels | Dairy Farmers Stadium | View |
| 18 March | Warriors | 16 – 28 | Canterbury Bulldogs | Mt Smart Stadium | View |
| 18 March | Sydney Roosters | 34 – 24 | Canberra Raiders | Allianz Stadium | View |
| 18 March | Penrith Panthers | 36 – 24 | South Sydney Rabbitohs | Centrebet Stadium | View |
| 19 March | Cronulla Sharks | 78 – 10 | Manly Sea Eagles | Toyota Stadium | View |
| Round 4 | |||||
| 23 March | Parramatta Eels | 20 – 36 | Penrith Panthers | Parramatta Stadium | View |
| 24 March | South Sydney Rabbitohs | 54 – 30 | Brisbane Broncos | Redfern Oval | View |
| 24 March | Warriors | 30 – 6 | Gold Coast Titans | Mt Smart Stadium | View |
| 24 March | St George Illawarra Dragons | 26 – 24 | Manly Sea Eagles | WIN Jubilee Oval | View |
| 24 March | North Queensland Cowboys | 12 – 32 | Cronulla Sharks | Dairy Farmers Stadium | View |
| 25 March | Melbourne Storm | 32 – 30 | Sydney Roosters | AAMI Park | View |
| 25 March | Canterbury Bulldogs | 20 – 32 | Newcastle Knights | ANZ Stadium | View |
| 26 March | Wests Tigers | 40 – 10 | Canberra Raiders | Campbelltown Stadium | View |
| Round 5 | |||||
| 30 March | Melbourne Storm | 16 – 36 | Newcastle Knights | AAMI Park | View |
| 30 March | Brisbane Broncos | 34 – 42 | St George Illawarra Dragons | Suncorp Stadium | View |
| 31 March | Penrith Panthers | 48 – 22 | Cronulla Sharks | Centrebet Stadium | View |
| 31 March | Sydney Roosters | 28 – 28 | Warriors | Allianz Stadium | View |
| 1 April | Gold Coast Titans | 20 – 60 | Canterbury Bulldogs | Skilled Park | View |
| 1 April | Wests Tigers | 36 – 24 | South Sydney Rabbitohs | Allianz Stadium | View |
| 1 April | Parramatta Eels | 52 – 20 | Manly Sea Eagles | Ringrose Park | View |
| 2 April | Canberra Raiders | 42 – 18 | North Queensland Cowboys | Canberra Stadium | View |
| Round 6 | |||||
| 6 April | South Sydney Rabbitohs | 26 – 24 | Canterbury Bulldogs | ANZ Stadium | View |
| 6 April | Wests Tigers | 30 – 46 | Brisbane Broncos | Allianz Stadium | View |
| 7 April | Gold Coast Titans | 12 – 40 | Sydney Roosters | Skilled Park | View |
| 7 April | Cronulla Sharks | 21 – 20 | St George Illawarra Dragons | Toyota Stadium | View |
| 8 April | Canberra Raiders | 32 – 28 | Warriors | Canberra Stadium | View |
| 8 April | Newcastle Knights | 44 – 24 | Parramatta Eels | Hunter Stadium | View |
| 8 April | North Queensland Cowboys | 26 – 34 | Melbourne Storm | Dairy Farmers Stadium | View |
| 9 April | Manly Sea Eagles | 0 – 44 | Penrith Panthers | Brookvale Oval | View |
| Round 7 | |||||
| 13 April | St George Illawarra Dragons | 36 – 16 | Newcastle Knights | WIN Jubilee Oval | View |
| 13 April | Brisbane Broncos | 12 – 40 | Canberra Raiders | Suncorp Stadium | View |
| 14 April | Melbourne Storm | 12 – 38 | Canterbury Bulldogs | AAMI Park | View |
| 14 April | Manly Sea Eagles | 28 – 24 | Gold Coast Titans | Brookvale Oval | View |
| 15 April | Warriors | 48 – 14 | South Sydney Rabbitohs | Mt Smart Stadium | View |
| 15 April | Cronulla Sharks | 20 – 22 | Parramatta Eels | Toyota Stadium | View |
| 15 April | Sydney Roosters | 40 – 18 | North Queensland Cowboys | North Sydney Oval | View |
| 15 April | Penrith Panthers | 24 – 40 | Wests Tigers | Centrebet Stadium | View |
| Round 8 | |||||
| 25 April | St George Illawarra Dragons | 24 – 28 | Sydney Roosters | Allianz Stadium | View |
| 25 April | Melbourne Storm | 18 – 26 | Warriors | AAMI Park | View |
| 27 April | Canterbury Bulldogs | 28 – 28 | Manly Sea Eagles | ANZ Stadium | View |
| 27 April | Brisbane Broncos | 8 – 23 | Gold Coast Titans | Suncorp Stadium | View |
| 28 April | South Sydney Rabbitohs | 34 – 14 | North Queensland Cowboys | ANZ Stadium | View |
| 29 April | Canberra Raiders | 54 – 12 | Cronulla Sharks | Canberra Stadium | View |
| 29 April | Parramatta Eels | 16 – 42 | Wests Tigers | Parramatta Stadium | View |
| 30 April | Newcastle Knights | 28 – 29 | Penrith Panthers | Hunter Stadium | View |
| Round 9 | |||||
| 4 May | Parramatta Eels | 22 – 58 | Canterbury Bulldogs | ANZ Stadium | View |
| 4 May | North Queensland Cowboys | 24 – 24 | St George Illawarra Dragons | Dairy Farmers Stadium | View |
| 5 May | Warriors | 34 – 10 | Brisbane Broncos | Mt Smart Stadium | View |
| 5 May | Gold Coast Titans | 6 – 34 | Wests Tigers | Skilled Park | View |
| 5 May | Penrith Panthers | 16 – 16 | Melbourne Storm | Centrebet Stadium | View |
| 6 May | Manly Sea Eagles | 16 – 34 | Canberra Raiders | Brookvale Oval | View |
| 6 May | Sydney Roosters | 22 – 28 | Newcastle Knights | Allianz Stadium | View |
| 7 May | South Sydney Rabbitohs | 36 – 36 | Cronulla Sharks | ANZ Stadium | View |
| Round 10 | |||||
| 11 May | Brisbane Broncos | 52 – 36 | Manly Sea Eagles | Suncorp Stadium | View |
| 12 May | Canterbury Bulldogs | 52 – 6 | Gold Coast Titans | Belmore Sports Ground | View |
| 12 May | Warriors | 26 – 18 | Sydney Roosters | Mt Smart Stadium | View |
| 12 May | Newcastle Knights | 28 – 28 | North Queensland Cowboys | Hunter Stadium | View |
| 13 May | Canberra Raiders | 62 – 30 | Parramatta Eels | Canberra Stadium | View |
| 13 May | Cronulla Sharks | 32 – 22 | Melbourne Storm | Toyota Stadium | View |
| 14 May | Penrith Panthers | 20 – 18 | St George Illawarra Dragons | Centrebet Stadium | View |
| South Sydney Rabbitohs | BYE | ||||
| Wests Tigers | BYE |
| Round 11 | |||||
| 18 May | Wests Tigers | 54 – 12 | Warriors | Leichhardt Oval | View |
| 19 May | North Queensland Cowboys | 20 – 26 | Penrith Panthers | Dairy Farmers Stadium | View |
| 20 May | Manly Sea Eagles | 26 – 28 | Sydney Roosters | Brookvale Oval | View |
| 20 May | St George Illawarra Dragons | 10 – 24 | South Sydney Rabbitohs | WIN Jubilee Oval | View |
| 21 May | Canterbury Bulldogs | 26 – 10 | Cronulla Sharks | ANZ Stadium | View |
| Brisbane Broncos | BYE | ||||
| Canberra Raiders | BYE | ||||
| Gold Coast Titans | BYE | ||||
| Melbourne Storm | BYE | ||||
| Newcastle Knights | BYE | ||||
| Parramatta Eels | BYE |
| Round 12 | |||||
| 25 May | South Sydney Rabbitohs | 24 – 36 | Canberra Raiders | ANZ Stadium | View |
| 25 May | Melbourne Storm | 10 – 30 | Brisbane Broncos | AAMI Park | View |
| 26 May | Newcastle Knights | 14 – 10 | Gold Coast Titans | Hunter Stadium | View |
| 26 May | St George Illawarra Dragons | 30 – 22 | Parramatta Eels | WIN Jubilee Oval | View |
| 27 May | Penrith Panthers | 28 – 20 | Manly Sea Eagles | Centrebet Stadium | View |
| 27 May | Wests Tigers | 36 – 38 | North Queensland Cowboys | Campbelltown Stadium | View |
| 28 May | Sydney Roosters | 20 – 24 | Canterbury Bulldogs | Allianz Stadium | View |
| Cronulla Sharks | BYE | ||||
| Warriors | BYE |
| Round 13 | |||||
| 1 June | Gold Coast Titans | 16 – 17 | North Queensland Cowboys | Skilled Park | View |
| 1 June | Manly Sea Eagles | 16 – 46 | St George Illawarra Dragons | Brookvale Oval | View |
| 2 June | Canberra Raiders | 6 – 15 | Wests Tigers | Canberra Stadium | View |
| 2 June | Canterbury Bulldogs | 10 – 32 | South Sydney Rabbitohs | ANZ Stadium | View |
| 3 June | Brisbane Broncos | 18 – 46 | Newcastle Knights | Suncorp Stadium | View |
| 3 June | Warriors | 30 – 8 | Melbourne Storm | Mt Smart Stadium | View |
| 4 June | Parramatta Eels | 24 – 36 | Cronulla Sharks | Parramatta Stadium | View |
| Penrith Panthers | BYE | ||||
| Sydney Roosters | BYE |
| Round 14 | |||||
| 8 June | Melbourne Storm | 12 – 6 | Wests Tigers | AAMI Park | View |
| 9 June | Newcastle Knights | 20 – 28 | Canberra Raiders | Hunter Stadium | View |
| 10 June | Cronulla Sharks | 18 – 42 | Gold Coast Titans | Toyota Stadium | View |
| 10 June | Sydney Roosters | 28 – 18 | Brisbane Broncos | Allianz Stadium | View |
| 11 June | Penrith Panthers | 14 – 10 | Warriors | Centrebet Stadium | View |
| Canterbury Bulldogs | BYE | ||||
| Manly Sea Eagles | BYE | ||||
| North Queensland Cowboys | BYE | ||||
| Parramatta Eels | BYE | ||||
| South Sydney Rabbitohs | BYE | ||||
| St George Illawarra Dragons | BYE |
| Round 15 | |||||
| 15 June | St George Illawarra Dragons | 38 – 24 | Canterbury Bulldogs | WIN Stadium | View |
| 15 June | North Queensland Cowboys | 28 – 16 | Brisbane Broncos | Dairy Farmers Stadium | View |
| 16 June | Cronulla Sharks | 18 – 24 | Warriors | Toyota Stadium | View |
| 16 June | Parramatta Eels | 8 – 24 | South Sydney Rabbitohs | ANZ Stadium | View |
| 17 June | Gold Coast Titans | 12 – 52 | Penrith Panthers | Skilled Park | View |
| 17 June | Wests Tigers | 18 – 40 | Sydney Roosters | Leichhardt Oval | View |
| 18 June | Manly Sea Eagles | 26 – 26 | Melbourne Storm | Brookvale Oval | View |
| Canberra Raiders | BYE | ||||
| Newcastle Knights | BYE |
| Round 16 | |||||
| 22 June | Brisbane Broncos | 34 – 32 | South Sydney Rabbitohs | Suncorp Stadium | View |
| 22 June | St George Illawarra Dragons | 16 – 26 | Gold Coast Titans | WIN Stadium | View |
| 23 June | Canterbury Bulldogs | 34 – 16 | Melbourne Storm | Lidcombe Oval | View |
| 23 June | North Queensland Cowboys | 22 – 38 | Canberra Raiders | Dairy Farmers Stadium | View |
| 23 June | Penrith Panthers | 24 – 12 | Parramatta Eels | Centrebet Stadium | View |
| 24 June | Sydney Roosters | 40 – 10 | Manly Sea Eagles | Allianz Stadium | View |
| 25 June | Newcastle Knights | 14 – 18 | Wests Tigers | Hunter Stadium | View |
| Cronulla Sharks | BYE | ||||
| Warriors | BYE |
| Round 17 | |||||
| 29 June | Brisbane Broncos | 24 – 30 | Cronulla Sharks | Suncorp Stadium | View |
| 30 June | Parramatta Eels | 42 – 28 | Newcastle Knights | Parramatta Stadium | View |
| 1 July | South Sydney Rabbitohs | 46 – 16 | Penrith Panthers | ANZ Stadium | View |
| 1 July | Warriors | 48 – 16 | North Queensland Cowboys | Mt Smart Stadium | View |
| 2 July | Canberra Raiders | 30 – 32 | St George Illawarra Dragons | Canberra Stadium | View |
| Canterbury Bulldogs | BYE | ||||
| Gold Coast Titans | BYE | ||||
| Manly Sea Eagles | BYE | ||||
| Melbourne Storm | BYE | ||||
| Sydney Roosters | BYE | ||||
| Wests Tigers | BYE |
| Round 18 | |||||
| 6 July | Wests Tigers | 16 – 22 | Canterbury Bulldogs | Allianz Stadium | View |
| 7 July | Melbourne Storm | 34 – 30 | Canberra Raiders | AAMI Park | View |
| 7 July | Gold Coast Titans | 22 – 38 | Warriors | Skilled Park | View |
| 8 July | South Sydney Rabbitohs | 24 – 16 | Newcastle Knights | ANZ Stadium | View |
| 8 July | Manly Sea Eagles | 24 – 22 | Parramatta Eels | Brookvale Oval | View |
| 9 July | Cronulla Sharks | 14 – 14 | Sydney Roosters | Toyota Stadium | View |
| Brisbane Broncos | BYE | ||||
| North Queensland Cowboys | BYE | ||||
| Penrith Panthers | BYE | ||||
| St George Illawarra Dragons | BYE |
| Round 19 | |||||
| 13 July | Brisbane Broncos | 22 – 38 | Warriors | Suncorp Stadium | View |
| 13 July | Canterbury Bulldogs | 26 – 18 | Parramatta Eels | ANZ Stadium | View |
| 14 July | Melbourne Storm | 32 – 16 | North Queensland Cowboys | AAMI Park | View |
| 14 July | Newcastle Knights | 16 – 17 | Manly Sea Eagles | Hunter Stadium | View |
| 14 July | Wests Tigers | 23 – 22 | Penrith Panthers | Campbelltown Stadium | View |
| 15 July | Canberra Raiders | 34 – 14 | Gold Coast Titans | Canberra Stadium | View |
| 15 July | St George Illawarra Dragons | 44 – 12 | Cronulla Sharks | WIN Stadium | View |
| 16 July | Sydney Roosters | 36 – 30 | South Sydney Rabbitohs | Allianz Stadium | View |
| Round 20 | |||||
| 20 July | Manly Sea Eagles | 22 – 48 | Canterbury Bulldogs | Brookvale Oval | View |
| 20 July | Gold Coast Titans | 29 – 16 | Brisbane Broncos | Skilled Park | View |
| 21 July | Warriors | 24 – 14 | Newcastle Knights | Mt Smart Stadium | View |
| 21 July | South Sydney Rabbitohs | 16 – 28 | St George Illawarra Dragons | ANZ Stadium | View |
| 21 July | Parramatta Eels | 22 – 28 | Melbourne Storm | Parramatta Stadium | View |
| 22 July | Cronulla Sharks | 36 – 28 | Canberra Raiders | Toyota Stadium | View |
| 22 July | Penrith Panthers | 38 – 20 | Sydney Roosters | Centrebet Stadium | View |
| 23 July | North Queensland Cowboys | 20 – 36 | Wests Tigers | Dairy Farmers Stadium | View |
| Round 21 | |||||
| 27 July | St George Illawarra Dragons | 24 – 12 | Melbourne Storm | WIN Stadium | View |
| 27 July | Sydney Roosters | 30 – 16 | Gold Coast Titans | Allianz Stadium | View |
| 28 July | Canterbury Bulldogs | 28 – 30 | North Queensland Cowboys | ANZ Stadium | View |
| 28 July | Cronulla Sharks | 30 – 24 | Penrith Panthers | Toyota Stadium | View |
| 29 July | Canberra Raiders | 36 – 28 | Newcastle Knights | Canberra Stadium | View |
| 29 July | South Sydney Rabbitohs | 36 – 30 | Wests Tigers | ANZ Stadium | View |
| 29 July | Manly Sea Eagles | 22 – 42 | Warriors | Brookvale Oval | View |
| 30 July | Brisbane Broncos | 42 – 26 | Parramatta Eels | Suncorp Stadium | View |
| Round 22 | |||||
| 3 August | Sydney Roosters | 16 – 28 | St George Illawarra Dragons | Allianz Stadium | View |
| 4 August | Melbourne Storm | 20 – 14 | Penrith Panthers | AAMI Park | View |
| 4 August | Newcastle Knights | 26 – 38 | Canterbury Bulldogs | Hunter Stadium | View |
| 4 August | North Queensland Cowboys | 22 – 24 | Manly Sea Eagles | Dairy Farmers Stadium | View |
| 5 August | Warriors | 10 – 40 | Cronulla Sharks | Mt Smart Stadium | View |
| 5 August | Canberra Raiders | 50 – 36 | Brisbane Broncos | Canberra Stadium | View |
| 5 August | Gold Coast Titans | 6 – 48 | South Sydney Rabbitohs | Skilled Park | View |
| 6 August | Wests Tigers | 26 – 16 | Parramatta Eels | Campbelltown Stadium | View |
| Round 23 | |||||
| 10 August | South Sydney Rabbitohs | 18 – 14 | Manly Sea Eagles | Bluetongue Stadium | View |
| 10 August | Melbourne Storm | 20 – 14 | Gold Coast Titans | AAMI Park | View |
| 11 August | Parramatta Eels | 12 – 42 | Sydney Roosters | Parramatta Stadium | View |
| 11 August | North Queensland Cowboys | 32 – 28 | Warriors | Dairy Farmers Stadium | View |
| 11 August | Wests Tigers | 10 – 6 | St George Illawarra Dragons | Allianz Stadium | View |
| 12 August | Penrith Panthers | 22 – 28 | Canberra Raiders | Centrebet Stadium | View |
| 12 August | Canterbury Bulldogs | 38 – 32 | Brisbane Broncos | ANZ Stadium | View |
| 13 August | Newcastle Knights | 44 – 24 | Cronulla Sharks | Hunter Stadium | View |
| Round 24 | |||||
| 17 August | Canterbury Bulldogs | 22 – 12 | Wests Tigers | ANZ Stadium | View |
| 17 August | Brisbane Broncos | 18 – 60 | Melbourne Storm | Suncorp Stadium | View |
| 18 August | Canberra Raiders | 44 – 20 | Sydney Roosters | Canberra Stadium | View |
| 18 August | Cronulla Sharks | 30 – 18 | South Sydney Rabbitohs | Toyota Stadium | View |
| 19 August | Warriors | 18 – 16 | Penrith Panthers | Mt Smart Stadium | View |
| 19 August | Gold Coast Titans | 34 – 32 | Parramatta Eels | Skilled Park | View |
| 19 August | Manly Sea Eagles | 30 – 18 | Newcastle Knights | Brookvale Oval | View |
| 20 August | St George Illawarra Dragons | 34 – 16 | North Queensland Cowboys | WIN Stadium | View |
| Round 25 | |||||
| 24 August | Canberra Raiders | 12 – 46 | Canterbury Bulldogs | Canberra Stadium | View |
| 24 August | Manly Sea Eagles | 22 – 29 | Brisbane Broncos | Brookvale Oval | View |
| 25 August | Penrith Panthers | 78 – 0 | Gold Coast Titans | Centrebet Stadium | View |
| 25 August | St George Illawarra Dragons | 28 – 30 | Warriors | WIN Stadium | View |
| 25 August | North Queensland Cowboys | 4 – 24 | Newcastle Knights | Dairy Farmers Stadium | View |
| 26 August | Sydney Roosters | 40 – 16 | Wests Tigers | Allianz Stadium | View |
| 26 August | South Sydney Rabbitohs | 54 – 6 | Parramatta Eels | ANZ Stadium | View |
| 27 August | Melbourne Storm | 24 – 12 | Cronulla Sharks | AAMI Park | View |
| Round 26 | |||||
| 31 August | Newcastle Knights | 26 – 50 | South Sydney Rabbitohs | Hunter Stadium | View |
| 31 August | Brisbane Broncos | 36 – 34 | Penrith Panthers | Suncorp Stadium | View |
| 1 September | Gold Coast Titans | 10 – 46 | Manly Sea Eagles | Skilled Park | View |
| 1 September | Canterbury Bulldogs | 36 – 28 | Sydney Roosters | ANZ Stadium | View |
| 1 September | Wests Tigers | 24 – 22 | Melbourne Storm | Leichhardt Oval | View |
| 2 September | Warriors | 26 – 12 | Canberra Raiders | Mt Smart Stadium | View |
| 2 September | Cronulla Sharks | 28 – 48 | North Queensland Cowboys | Toyota Stadium | View |
| 2 September | Parramatta Eels | 28 – 38 | St George Illawarra Dragons | ANZ Stadium | View |